Oxbryta Sickle Cell Drug Lawsuit

Patients Taking Oxbryta Have Increased Risk of Having VOC

Increased Risk of Injury after Taking Oxbryta

A lawsuit has been filed against Pfizer’s wholly owned subsidiary, Global Blood Therapeutics, Inc., claiming that the medication Oxbryta caused significant injury. The lawsuit alleges that the company failed to warn of serious risks, leading to severe harm. 

What is Oxbryta?

Oxbryta, or voxelotor, is a medication used to treat sickle cell disease (SCD) in individuals aged four and older. It works by preventing the polymerization of hemoglobin S, helping red blood cells maintain their normal shape and improving oxygen transport. This reduces complications like anemia and vaso-occlusive crises. Common side effects include headache, diarrhea, and nausea.

What is Sickle Cell Disease?

Sickle cell disease is a genetic blood disorder where red blood cells become are misshaped, typically crescent- or “sickle”-shaped due to a gene mutation that affects the hemoglobin molecule. This abnormal shape can lead to blockages in blood vessels, causing pain and potential organ damage due to impaired blood flow.

What is a VOC or Vaso-Occlusive Crisis?

A Vaso-Occlusive Crisis (VOC) is a painful complication commonly seen in individuals with sickle cell disease. It occurs when the abnormally shaped sickle cells block blood flow in small blood vessels, leading to reduced oxygen delivery to tissues.

Symptoms and injuries that can result from Vaso-Occlusive Crises (VOCs):

  • Severe, sharp pain (commonly in the bones, chest, abdomen, or joints)
  • Swelling in hands and feet (dactylitis)
  • Fever
  • Fatigue or weakness
  • Shortness of breath or difficulty breathing
  • Acute chest syndrome (chest pain, fever, and lung complications)
  • Stroke
  • Organ damage (kidneys, liver, spleen)
  • Tissue damage due to lack of oxygen
  • Risk of infection due to spleen damage

Oxbryta Lawsuits

Drug manufacturers are responsible for ensuring the safety and efficacy of their products before marketing them for public consumption. Failure to do so is considered negligent and grounds for litigation. The attorneys of Aylstock, Witkin Kreis & Overholtz handle litigation across the United States for victims injured by defective pharmaceuticals and medical devices. We have successfully represented and obtained substantial compensation for thousands of patients who have been harmed by prescription drugs.

How AWKO Can Help With Injuries Related to Oxbryta

For over 25 years, the AWKO firm has successfully represented more than 250,000 individuals in cases involving injuries caused by dangerous drugs and medical devices. Committed to fighting for justice, AWKO passionately advocates for victims’ rights, ensuring they receive the compensation they deserve.

If you or a loved one have been diagnosed with sickle cell disease and have experienced serious side effects or complications from taking Oxbryta, including pain crises, organ damage, or other related injuries, please call us today at 1-877-810-4808 or use the “Free Case Evaluation” form below. We are here to provide you with more information about your legal rights.

At AWKO, We Stand With Sickle Cell Warriors

Many of our clients are not just patients—they’re sickle cell warriors and survivors who show immense strength every day. We honor their resilience and are committed to fighting for justice on their behalf. To learn more about the community and find support, visit Sickle Cell Warriors.

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